Analysis of clinical characteristics and prognosis of meningovascular syphilis
10.16571/j.cnki.1008-8199.2016.02.012
- VernacularTitle:脑膜血管型神经梅毒的临床分析
- Author:
Ling TIAN
;
Wenhua LIU
;
Lulu XIAO
;
Haixia ZHANG
;
Qinqin CAO
;
Xin CHEN
;
Minhui DAI
;
Gelin XU
- Publication Type:Journal Article
- Keywords:
Meningovascular syphilis;
Clinical characters;
Prognosis
- From:
Journal of Medical Postgraduates
2016;(2):178-181
- CountryChina
- Language:Chinese
-
Abstract:
Objective Meningovascular syphilis is the intima inflammation of blood vessels caused by the syphilitic infec-tion, which is associated with the occurrence of ischemic stroke.The study analyzed the clinical, imaging features and prognosis for meningovascular syphilis so as to improve its diagnosis and treatment. Methods 14 patients diagnosed with meningovascular syphilis were collected prospectively from December 2007 to March 2015 in the neurological department of Jinling Hospital.The patients were followed for a period of 21.5(range 10.2~37.9)months,and the prognosis were evaluated. Results Patients with meningovascular syphilis presented with dizziness, hemiplegia, hemidysesthesia and cognitive decline.Lesions showed multiple, scattered on MR ima-ging, intracranial vascular stenosis was seen in the CTA/MRA, and the laboratory examination had characteristic changes.With a large dose and sufficient courses of penicillin treatment, meningovascular syphilis may hopefully get predominant effects.78.57%patients got good prognosis(modified Rankin Scale ,mRS≤2)at 3 months and 85.71% patients got goodlong-term prognosis(mRS≤2). Conclusion Meningovascular syphilis was usually presented as acute onset, lacks the specific clinical and neuroimaging manifesta-tions.Most patients has favourable prognosis after treatment of syphilis with full course of penicillin.
