Study of T lymphocyte subsets in infectious mononucleosis syndrome
- VernacularTitle:T 淋巴细胞亚群检测在传染性单核细胞增多症中的价值研究
- Author:
Wenyan ZHAI
;
Jinbiao ZHANG
;
Lifang WANG
;
Juan LI
- Publication Type:Journal Article
- Keywords:
Infectious mononucleosis syndrome;
EB virus;
T lymphocyte subsets
- From:
Journal of Chinese Physician
2015;(z2):22-24
- CountryChina
- Language:Chinese
-
Abstract:
Objective T lymphocyte subsets in children with characteristics observed with infec-tious mononucleosis (infectious mononucleosis,IM),to explore its reference value.Methods January 2011 to December 2014 during a pediatric door altogether 115 cases of hospitalized children were divided in-to three groups,51 cases of IMgroup,33 atypical group,31 patients flyers syndrome,selecting outpatient healthy children as 101 cases the control group.For each group T lymphocyte subsets:CD3 + CD4 +,CD3 +CD8 +,CD4 +/CD8 + ratio,analyze the differences between the groups was significant.Results Compared four groups of T lymphocyte subsets (CD3 +,CD3 +CD4 +,CD3 +CD8 +,CD4 +/CD8 + ratio)change char-acteristics,IMgroup,atypical group,flyers syndrome group and the control group,the difference was sta-tistically significance (P <0.05),presence prompts patients significant immune dysfunction;children IM group than in the atypical group,flyers syndrome group CD3 +,indicators of changes in CD3 +CD4 +,CD3 +CD8 +,CD4 +/CD8 + ratio and other more obvious The difference was statistically significant (P <0.05), described IMgroup of children was more severe immune dysfunction;atypical combination Flyer syndrome group,the difference was not statistically significant (P >0.05),two groups of children described in T there was no significant difference in lymphocyte immune.Conclusions T lymphocyte subsets have some reference value in the differential diagnosis of IM,and prompt clinical attention to EB virus infection in chil-dren whose immune function,can help prevent and treat.
