The value of three-dimensional Doppler angiography in the differentiation of benign and malignant thyroid nodules
10.3969/j.issn.1007-3969.2016.01.010
- VernacularTitle:三维能量多普勒超声血管成像在甲状腺结节良恶性诊断中的应用价值
- Author:
Wenbo LI
;
Bo ZHANG
;
Qingli ZHU
;
Yuxin JIANG
;
Jian SUN
;
Qing ZHANG
;
Meng YANG
;
Jianchu LI
- Publication Type:Journal Article
- Keywords:
Thyroid nodule;
Three-dimensional power Doppler angiography;
Diagnosis
- From:
China Oncology
2016;(1):60-66
- CountryChina
- Language:Chinese
-
Abstract:
Background and purpose:Three-dimensional power Doppler angiography (3D-PDA) is a new technique to investigate the vessels in the organs, but the research in thyroid is limited. The purpose of this research was to investigate three-dimensional power Doppler angiography (3D-PDA) in differentiating malignant from benign thyroid nod-ules.Methods:This study prospectively evaluated 103 lesions in 94 patients who were scheduled for surgery. The patients underwent preoperative 3D-PDA scanning. Analysis of the 3D-PDA characteristics includes blood flow pattern, the num-ber of blood vessels, the shape of vessels, the spatial distribution of the vessels, the existence of rich local blood flow within nodules or in the parenchyma surrounding the nodules. This study also analyzed the difference between the benign lesions and the malignant lesions.Results:There were 50 benign lesions and 53 malignant lesions. The sensitivity and specificity of irregular vessels, the asymmetry spatial distribution, rich local blood flow within nodules or in the parenchyma surround-ing the nodules were 64.2%, 96.0%; 56.0%, 88.0%; 54.7%, 96.0%; 60.4% and 94.0%, respectively. The sensitivity, speci-ficity, positive predictive value, negative predictive value and accuracy of 3D-PDA were 83.0%, 94.0%, 93.6%, 83.9% and 90.3%, respectively.Conclusion:3D-PDA provides a useful tool to investigate vascularization of thyroid leisions.This technique is feasible for clinical application and plays an important role in diagnosis of thyroid nodules.
