Etiology of endophthalmitis and drug sensitivity analysis
10.3969/j.issn.1673-4130.2016.03.011
- VernacularTitle:眼内炎的病原学及药敏分析
- Author:
Jian SUN
- Publication Type:Journal Article
- Keywords:
endophthalmitis;
etiology;
drug sensitivity
- From:
International Journal of Laboratory Medicine
2016;(3):316-318
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the common pathogens of endophthalmitis and their drug sensitivity .Methods 184 patients with endophthalmitis were selected .The aqueous humor or vitreous body was taken to inoculate in broth ,blood agar and potato dex‐trose agar medium for conducting bacterial and fungal culture .The K‐B method was adopted to conduct the drug sensitivity test .Re‐sults Among 184 cases ,9 cases were the mixed infection and 193 strains of bacteria were co‐cultured .Among them ,gram‐positive bacteria infection was most common ,108 strains were detected ,accounting for 55 .96% ,followed by gram‐negative bacteria ,63 strains were detected ,accounting for 32 .64% ,the detected fungi were less (22 strains) ,accounting for 11 .40% .The cultured gram‐positive bacteria were most sensitive to cefoperazone and cefuroxime both with the sensitivity of 87 .96% ,at the same time ,levo‐floxacin and cefazolin showed good sensitivity ,with the sensitivity of over 75% ,while the sensitivity to lomefloxacin was low ,only 50 .00% .Gram‐negative bacteria had highest sensitivity to lomefloxacin ,reaching 100 .00% ,in addition the sensitivity to ciprofloxa‐cin and ofloxacin also reached 87 .30% and 88 .89% ,while the sensitivity to cefuroxime ,ceftazidime and cefazolin was lower ,which were only 38 .10% ,39 .68% and 44 .44% respectively .Conclusion The infection types of pathogens should be comprehensively considered according to the causes of endophthalmitis occurrence .The combined medication should be selected during the empiric medication process after suffering from endophthalmitis .
