The Research Progress of Mechanism of Astragalus Polysaccharides Treatment of Asthma and Prospects
10.16466/j.issn1005-5509.2016.01.021
- VernacularTitle:黄芪多糖治疗哮喘的机制研究进展及展望
- Author:
Hao LING
;
Xia ZHAO
- Publication Type:Journal Article
- Keywords:
Astragalus Polysaccharide;
asthma gene;
inflammation;
airway remodeling;
review
- From:
Journal of Zhejiang Chinese Medical University
2016;(1):72-74
- CountryChina
- Language:Chinese
-
Abstract:
Objective] The mechanism of astragalus polysaccharides treatment of asthma was discussed. [Methods]Through the domestic and foreign about traditional Chinese medicine monomer astragalus polysaccharide on IL-4, IL-10 and other cytokines and inflammatory infiltrates aspects such as the Th1/Th2 balance, smooth muscle actin and airway mucus in the airway remodeling and asthma related gene research literature summary. [Results] Improve airway inflammation astragalus polysaccharides from activation and inhibition EOS EOS infiltration reduction, regulating Th1/Th2 imbalance, so Th0 cells to Th1 cell differentiation, and inhibiting the release of inflammatory cytokines and other aspects, APS can reduce airway hyper-responsiveness mitigate aspects peribronchial infiltration of eosinophils and airway smooth muscle cells induced byα-SMA expression and other high alleviate airway remodeling. [Conclusion] The influence of astragalus polysaccharide on asthma gene research will lay the basis for study of the mechanism of treatment of asthma, monomer research provides new ideas for traditional Chinese medicine.
