A case of brucella endocarditis with spondylitis in a patient with multiple myeloma.
- Author:
Yung Un KANG
1
;
Young Sun JUNG
;
Kyung Hwa PARK
;
Sook In JUNG
;
Jong Hee SHIN
;
Byung Hee ANH
;
Kwan Soo KO
Author Information
1. Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea. medkid@dreamwiz.com
- Publication Type:Case Report
- Keywords:
Brucellosis;
Endocarditis;
Spondylitis
- MeSH:
Abscess;
Anti-Bacterial Agents;
Aortic Valve;
Biopsy;
Bone Marrow;
Brucella;
Brucella abortus;
Brucellosis;
Endocarditis;
Epidural Abscess;
Fever;
Humans;
Low Back Pain;
Magnetic Resonance Imaging;
Multiple Myeloma;
Pancytopenia;
Sequence Analysis, DNA;
Spine;
Spondylitis
- From:Korean Journal of Medicine
2008;74(5):561-565
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Brucella endocarditis is a rare complication, but it is responsible for the majority of deaths related to this illness. A 67 year-old man presented with complaints of fever and lower back pain that he had experienced during the previous four weeks. The laboratory finding showed pancytopenia and an inverted total protein/globulin ratio. Multiple myeloma was diagnosed by bone marrow biopsy and serum electrophorosis. The spine MRI scan demonstrated spondylitis with epidural abscess (L5-S1). On the echocardiographic examination, there was vegetation on the right coronary cusp of the aortic valve and perivalvular abscess. The blood isolate was confirmed as Brucella abortus by using DNA sequencing of the 16S rRNA and the omp2a and omp2b genes. The clinical manifestations improved after appropriate antibiotics and aortic valve replacement. We describe here the first Korean case of human brucella endocarditis that was treated by valve replacement.
