Performance validation of Centaur XP automatic chemiluminescence system in detection of insulin and C-peptide
10.3969/j.issn.1673-4130.2016.03.022
- VernacularTitle:CentaurXP全自动化学发光系统检测胰岛素及C肽性能验证
- Author:
Zhen LI
;
Furong LIU
- Publication Type:Journal Article
- Keywords:
insulin;
C peptide;
chemiluminescence;
performance verification
- From:
International Journal of Laboratory Medicine
2016;(3):342-343
- CountryChina
- Language:Chinese
-
Abstract:
Objective To verify the performance of the ADVIA Centaur XP automatic chemiluminescence analyzer produced by the Siemens company in quantitative detection of serum insulin (IRI) and C‐peptide(CpS) .Methods The blood samples from 40 in‐dividuals undergoing the physical examination were detected for calculating the imprecision and bias of IRI and CpS .The linear range of IRI was verified .The reference range of IRI and CpS was verified .Results The intra‐batch variable of coefficient of IRI and CpS was less than 6 .25% ,the inter‐batch imprecision were less than 8 .33% ;the bias of IRI and CpS detection was less than 12 .5% ;the linear range of IRI was 0 .50 - 307 .76 mIU /L ;the detection results of 40 serum samples showed that all IRS were with‐in the reference range provided by manufacturer ,the results in 2 cases of CpS was out of the reference range provided by manufac‐turer ,indicating that it conformed to the relevant requirements .Conclusion The main performance of the ADVIA Centaur XP auto ‐matic chemiluminescence analyzer for detecting IRS and CpS meets the requirements ,which could be used for clinical detection .
