Association of abnormal bone metabolism markers and risk of coronary heart disease in elder women patients
10.3969/j.issn.1671-8348.2016.03.019
- VernacularTitle:老年女性患者骨代谢指标异常与冠心病的相关性研究
- Author:
Pan GAO
;
Gang TANG
;
Jun LONG
;
Ting LU
;
Hang XIAO
;
Liangyi SI
- Publication Type:Journal Article
- Keywords:
aged;
women;
coronary heart disease;
bone metabolism
- From:
Chongqing Medicine
2016;(3):348-350
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the correlation of bone metabolism levels and risk of coronary heart disease in elder women patients .Methods A total of 163 elder women patients were divided into three group:CON group ,CAD group ,and CHD group .We explored related atherosclerosis risk factors and factors related to bone metabolism .Results Compared with CON group ,there was no statistical significance in CAD group in factors related to bone metabolism(P>0 .05) .In CHD group ,serum 25‐OH‐Vitamin D significantly decreased and β‐C‐terminal telopeptide of type Ⅰ collagen significantly increased compared with CON group(P<0 .05) .Compared with CAD group ,the serum 25‐OH‐Vitamin C also significantly decreased andβ‐C‐terminal telopeptide of type Ⅰcollagen significantly increased(P< 0 .05) .Spearman correlation analysis showed that BMI ,HDL‐C ,triglycerides ,LDL‐C ,blood glucose and 25‐OH‐Vitamin D were correlated with coronary heart disease .With coronary heart disease as the dependent variable , the results showed lower LDL‐C ,25‐OH‐Vitamin D had independent predictive value for the risk coronary heart disease .Conclusion Lower 25‐OH‐Vitamin D levels in elder patients were positively correlated with coronary heart disease ,and it might also be an in‐dependent predictor .
