To study the influence of Madopar for serotonin in platelet of Parkinson's disease patients
- VernacularTitle:美多芭对帕金森病患者血小板中五羟色胺影响的临床研究
- Author:
Yongchun WANG
;
Zhao WANG
;
Tongtong LIU
- Publication Type:Journal Article
- Keywords:
Parkinson's disease;
Madopar;
Serotonin;
Platelet;
High performance liquid chromatography
- From:
Chinese Journal of Postgraduates of Medicine
2015;38(z1):27-28
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the influence of madopar for 5-HT in platelet of Parkinson's disease patients.Methods To observe 5-HT in platelet of 35 PD cases in our hospital who take Madopar in one year.At the same time,to observe the mental symptoms change of every case before and after the treatment.Result Madopar can significantly lower the 5-HT of platelet in one year treatment,and HAMD score results show that Madopar significantly higher before treatment.Conclusion Madopar can damage serotonin neurons in the brain,which may enhance the patients with depressive symptoms.
