The clinical application of absorbable internal fixation system in maxillofacial fractures：systematic review and Meta-analysis
10.3969/j.issn.2095-4344.2015.52.026
- VernacularTitle:可吸收内固定系统在颌面部骨折中应用的系统评价与Meta分析
- Author:
Hanghang LIU
;
Chenzhou WU
;
Weiyi PAN
;
Zhifei SU
;
Zexi DUAN
;
Long SHI
;
Chunjie LI
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2015;(52):8509-8516
- CountryChina
- Language:Chinese
-
Abstract:
BACKGROUND:There are numerous clinical studies on comparing absorbable internal fixation system and titanium metal internal fixation system in maxilofacial fractures; however, the systematic reviews and Meta-analysis in this field are rare. OBJECTIVE:To compare the clinical effect of absorbable internal fixation system and titanium internal fixation system in maxilofacial fractures through systematic review and Meta-analysis. MATERIALS AND METHODS:The randomized controled trials and controled clinical trials regarding the application of absorbable internal fixation system and titanium internal fixation system in maxilofacial fractures were electronicaly retrieved from Medline, Embase, the Cochrane Central Register of Controled Trials, China Biology Medicine disc, and China Academic Journal Network Publishing Database using the keywords. Meta-analysis was conducted using Revman 5.3 software. RESULTS AND CONCLUSION:Thirteen clinical studies were included, and totaly 1 718 patients were involved. The Meta-analysis results showed that the removal rate of implants in the absorbable internal fixation system group was significantly lower than that in the titanium internal fixation group (P=0.000 2); there were no significant differences in the healing rate of fracture I stage, the incidence of insufficient fixation in fracture site and the incidence of long-term complications between these two groups. These results demonstrate that the efficiency and safety of absorbable internal fixation system in maxillofacial fracture is satisfactory, and can reduce the proportion of secondary surgical removal of the implant. More randomized controlled trials should be conducted to confirm this conclusion.
