Progress of Research on Stress-related Intestinal Barrier Dysfunction
10.3969/j.issn.1008-7125.2016.01.011
- VernacularTitle:应激相关肠屏障功能损伤的研究进展
- Author:
Xiaoteng WANG
;
Chaoying CHEN
;
Meng ZHANG
;
Bin Lü
- Publication Type:Journal Article
- Keywords:
Stress;
Intestinal Barrier Function;
Permeability
- From:
Chinese Journal of Gastroenterology
2016;(1):55-58
- CountryChina
- Language:Chinese
-
Abstract:
Intestinal barrier is formed by intestinal mucous layer,epithelial cells,cellular tight junction,enterocyte membrane,submucosal lamina propria and immunologic factors,and plays a pivotal role in maintaining gastrointestinal function. Different types of stress can induce intestinal barrier dysfunction and increased intestinal permeability,leading to a series of gastrointestinal diseases. This article reviewed the progress of research on pathological changes and mechanism of stress-related intestinal barrier dysfunction.