Research progress on enrichment and isolation of circulating tumor cells using immunomagnetic separation based microfluidic technology
10.3760/cma.j.issn.1009-9158.2016.01.016
- VernacularTitle:基于免疫磁分离的微流控技术在循环肿瘤细胞富集分离中应用的研究进展
- Author:
Fulai LI
;
Pingfeng SUN
;
Xiaolin HUANG
;
Fan LI
;
Hengyi XU
- Publication Type:Journal Article
- Keywords:
Neoplastic cells,circulating;
Microfluidic analytical techniques;
Immunomagnetic separation
- From:
Chinese Journal of Laboratory Medicine
2016;(1):64-67
- CountryChina
- Language:Chinese
-
Abstract:
Circulating tumor cells ( CTCs ) exists in peripheral blood of patients with a variety of malignant tumors , the accurate detection of CTCs helps early detection of cancer , and can be used to guide individualized treatment of cancer patients , rapid assessment of tumor chemotherapy drugs and detection of tumor recurrence .However , the CTCs in peripheral blood of cancer patients were extremely low , their detection requires efficient and specific enrichment and separation methods .The new microfluidic technology can accurately control the microliquid preciously , combined with the immunomagnetic separation technology , has been applied in detecting CTCs , which can save the blood samples of CTCs , has the advantages of simple operation , fast sorting speed , high specificity and high purity .
