Diagnostic value of dobutamine-stressed cardiac morphing myocardial perfusion imaging for coronary artery disease in middle-aged patients
10.3760/cma.j.issn.2095-2848.2016.01.013
- VernacularTitle:多巴酚丁胺负荷心肌灌注三维重塑对中年冠心病患者的诊断价值
- Author:
Cheng CHANG
;
Wenhui XIE
;
Bei LEI
;
Lihua WANG
;
Ruogu LI
- Publication Type:Journal Article
- Keywords:
Coronary disease;
Tomography,emission-computed,single-photon;
Image process-ing,computer-assisted;
Dobutamine;
MIBI
- From:
Chinese Journal of Nuclear Medicine and Molecular Imaging
2016;(1):54-58
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the diagnostic value of dobutamine?stressed cardiac morphing ( CM) MPI ( CMMPI) for coronary artery disease ( CAD) in middle?aged patients. Methods A total of 97 middle?aged patients (52 males, 45 females, age 40-65 (52.98±7.74) years) from March 2011 to Febru?ary 2015 with chest distress, cardiopalmus and chest pain symptoms ( suspected CAD) were retrospectively studied. Informed consents were signed by patients before examination. All patients underwent one?day dobu?tamine?stressed/rest CMMPI and CAG within one month. The diagnostic value of CMMPI was assessed and compared with CAG. Results CMMPI revealed 42 abnormal cases and 9 normal cases in 51 cases with cor?onary artery stenosis by CAG. CMMPI found 11 abnormal cases and 35 normal cases in 46 cases with normal coronary artery by CAG. In comparison with CAG, the sensitivity, specificity, accuracy, positive predictive value and negative predictive value of CMMPI were 82.35%(42/51), 76.09%(35/46), 79.38%(77/97), 79.25%(42/53)and 79.55%(35/44) respectively. The side effect was slight and transient with an inci?dence of 82.47%(80/97). Conclusion The dobutamine?stressed CMMPI has an important value for the diagnosis of CAD and the assessment of myocardial damage in middle?aged patients.
