Molecular identification of Paragonimus heterotremus from different hosts in Vietnam using mitochondrial genetic markers
- Author:
Le Thanh Hoa
- Publication Type:Journal Article
- Keywords:
Paragonimus heterotremus
- MeSH:
Molecular Diagnostic Techniques;
Paragonimus;
Genome, Mitochondrial
- From:Journal of Vietnamese Medicine
2004;296(3):1-9
- CountryViet Nam
- Language:Vietnamese
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Abstract:
By molecular identification and using mitochondrial genetic markers, the results showed that different forms of lung fluke in Vietnam, including adult fluke from human, dogs, cats and Potamicus sp. rock crab, have been identified as Paragonimus heteotremus. Molecular-based analysis on 390 nucleotides of the cytochrome oxidase gene revealed that Paragonimus heterotremus of Vietnam from all forms showed high identity to the Chinese and Thai strains. (99.0 -99.2% nucleotide and 97-100% amino acid). Phylogenetic analysis uniquely placed the Vietnamese Paragonimus sp to the group of P.heterotremus of Chinese and Thai origin. Thus, P.heterotremus is offically identified from most of the natural and experimental hosts in Vietnam
