Feasibility of quantitative analysis of contrast-enhanced ultrasonography in evaluation of acute rejection of transplanted liver
10.3760/cma.j.issn.1004-4477.2016.02.011
- VernacularTitle:超声造影定量分析评估移植肝急性排异的诊断价值
- Publication Type:Journal Article
- Keywords:
Contrast-enhanced ultrasonography;
Liver transplantation;
Acute rejection
- From:
Chinese Journal of Ultrasonography
2016;25(2):136-139
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the feasibility of contrast‐enhanced ultrasonography (CEUS) in the evaluation of acute rejection of transplanted liver and screening of quantitative parameters . Methods Twenty‐six patients with transplanted liver were recruited in the study ,including 16 patients with acute rejection in transplanted liver as the study group ,10 patients without any complications in graft as the control group .All patients were examined with CEUS and the dynamic images of CEUS (at least 2 minute) were analyzed off line . Regions of interest were drawn in the liver parenchyma to get time‐intensity curve and quantitative parameters . Intrahepatic transit time was also calculated . All parameters were compared between the two groups . Results In group with graft acute rejection ,the hepatic transit time including hepatic artery‐hepatic vein transit time ( HA‐HVTT) and portal vein‐hepatic vein transit time( PV‐HVTT) were (6 .12 ± 2 .53)s and (3 .00 ± 2 .62)s ,respectively ,and significantly shorter than those in group without acute rejection [(14 .01 ± 3 .31) s and (9 .60 ± 3 .51) s , P < 0 .05] . The time to peak( TTP) of liver parenchyma was prolonged to (121 .06 ± 31 .13) s as the acute rejection occurred ,while the according time was (64 .87 ± 33 .92) s in group without rejection ,which showed a statistical difference between the two groups ( P < 0 .05) . Conclusions Quantitative analysis of CEUS can provide information of rejection of transplanted liver .
