Autosomal dominant polycystic kidney disease in children's early identification and outcome
10.3760/cma.j.issn.2095-428X.2016.05.001
- VernacularTitle:儿童常染色体显性遗传性多囊肾病的早期识别及转归
- Author:
Changchun CAO
- Publication Type:Journal Article
- Keywords:
Autosomal dominant polycystic kidney disease;
Early identification;
Outcome
- From:
Chinese Journal of Applied Clinical Pediatrics
2016;31(5):321-324
- CountryChina
- Language:Chinese
-
Abstract:
Autosomal dominant polycystic kidney disease( ADPKD)is the most common hereditary renal disease,which has an incidence of 1 / 1 000 to 1 / 500 in live births,was characterized by renal enlargement along with renal tubular cystic dilatation,approximately half of affected individuals reach end stage renal disease(ESRD)by 60 years of age,accounting for 7% - 10% of patients with ESRD. ADPKD could be diagnosed in children and even in ute-ro,early identification and intervention in children would ameliorate the progression of ADPKD to ESRD. Therefore,it is imperative for pediatricians to recognize the early clinical manifestations and outcome of the disease. The aim of this re-view will focus on the early identification,management and outcome in childhood.
