Human leukocyte antigen II typing of neuromyelitis optica

VernacularTitle:视神经脊髓炎的人类白细胞Ⅱ类抗原分型
Author: Ya ZHANG ; Suyue PAN ; Dongmei WANG ; Honghao WANG
Publication Type:Journal Article
Keywords: Neuromyelitis optica; Multiple sclerosis; Human leukocyte antigen
From: Chinese Journal of Primary Medicine and Pharmacy 2016;23(7):1108-1110
CountryChina
Language:Chinese
Abstract: Neuromyelitis optica ( NMO) is an idiopathic autoimmune inflammatory disorder of the central nervous system ( CNS) that predominantly affects the optic nerves and spinal cord.It is especially common in Asia. An association between NMO and other autoimmune diseases has been frequently reported, which is different from multiple sclerosis( MS) ,this phenomenon may due to different genetic background between these two diseases.There are reports on different populations to make this clear,which showed human leukocyte antigen( HLA) class II distribu-tion was unique entity different between NMO and MS or healthy controls,this would be a great help to make clear the mechanism underlying NMO pathogenesis.