Discussing viral load levels after HIV/AIDS merges HBV/HCV infection and its relationship with T lymphocytes
10.3969/j.issn.1671-8348.2016.07.015
- VernacularTitle:HIV／AIDS合并HBV／HCV感染病毒载量水平及与T淋巴细胞相关性的探讨
- Author:
Ruyi ZHANG
;
Jing YOU
;
Weibo YANG
;
Shaofeng RAO
- Publication Type:Journal Article
- Keywords:
hepatitis B virus;
hepatitis C virus;
HIV/AIDS;
HIV RNA;
T lymphocyte
- From:
Chongqing Medicine
2016;45(7):912-914
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the viral load levels after HIV/AIDS merges HBV/HCV infection and its relationship with T lymphocytes .Methods HIV RNA ,HBV DNA ,HCV RNA ,CD4+ T lymphocyte frequency ,CD8+ T lymphocyte frequency ,CD4/CD8 measured in HIV/AIDS simple infection group ,mixed HIV/HBV infection group and mixed HIV/HCV infection group .Ana‐lyze relationship of T lymphocyte and HIV RNA ,the correlation of HBV DNA/HCV RNA ,HIV RNA ,CD4+ T lymphocyte fre‐quency ,CD8+ T lymphocyte frequency ,CD4/CD8 .Results CD4+ T lymphocyte frequency of HIV/AIDS simple infection group , mixed HIV/HBV infection group and mixed HIV/HCV infection group showed negative correlated with their respective group′s HIV RNA(P<0 .05);CD8+ T lymphocyte frequency of HIV/AIDS simple infection group and mixed HIV/HBV infection group showed negative correlated with their respective group′s HIV RNA(P<0 .05);CD4/CD8 of HIV/AIDS simple infection group , mixed HIV/HBV infection group and mixed HIV/HCV infection group show negative correlated with their respective group′s HIV RNA(P<0 .05) .Conclusion T lymphocyte of HIV/AIDS patients drop faster ,leading to high viral load of HIV RNA ,HBV DNA and accelerating HIV disease progress with HBV infection .T lymphocyte of HIV/AIDS patients with HBV infection drop faster than with HCV infection .
