Determination of Residual Carbendazim in Honeysuckle Flowers by LC-MS/MS
- VernacularTitle:LC-MS/MS法测定金银花中多菌灵的残留量
- Author:
Jun ZHU
;
Qinhua CHEN
;
Peng LI
;
Lin XIONG
;
Fuchao CHEN
- Publication Type:Journal Article
- Keywords:
Honeysuckle flowers;
Carbendazim;
LC-MS/MS
- From:
China Pharmacist
2016;19(4):664-666
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To establish a rapid and sensitive method for the determination of carbendazim in honeysuckle flowers by LC-MS/MS. Methods:The sample was extracted by acetic ether. The mass spectrometer was operated in the positive ionization elec-trospray ( ESI) mode using selection ion monitoring ( SIM) . The transition m/z 192→160 was used to quantify carbendazim. Results:The method had a satisfactory linearity within the range of 50-5 000 ng·ml-1 for carbendazim (r=0. 999 4), the limit of detection (LOD) was 2. 0 ng·ml-1, and the mean recovery was 93. 2%. Conclusion:The method of LC-MS/MS is sensitive, simple and ac-curate,which is proved to be suitable for the determination of carbendazim in honeysuckle flowers.
