Curative Effect of Xiaocuo Decoction Combined with Vitamin A in the Treatment of Acne Vulgaris
- VernacularTitle:中药消痤汤联合维A酸治疗寻常性痤疮疗效观察
- Author:
Ping XU
;
Mingsheng GU
- Publication Type:Journal Article
- Keywords:
Xiaocuo decoction;
Erythromycin ethylsuccinate;
0. 025％ Tretinoin cream;
Acne vulgaris
- From:
China Pharmacist
2016;19(4):741-742
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the clinical efficacy and safety of traditional Chinese medicine Xiaozuo decoction combined with 0. 025% vitamin A for external use in the treatment of acne vulgaris. Methods:Totally 86 patients with acne vulgaris were randomly di-vided into the treatment group and the control group with 43 ones in each. The treatment group was treated with Xiaocuo dcoction, 1 dose/day, and the control group was orally treated with erythromycin ethylsuccinate, 0. 25g per time, 3 times per day. The treatment course was 6 weeks, and both groups were treated with 0. 025% tretinoin cream once every night. The clinical efficacy and adverse drug reactions were compared between the two groups. Results:The obvious effective rate of the treatment group and the control group was 69. 77% and 41. 86%, respectively, and the total effective rate was 88. 37% and 69. 77%, respectively. There was significant difference in the obvious effective rate between the two groups (P<0. 01), while there was significant difference in the total effective rate between the two groups (P<0. 05). Recurrence rates of two groups were 10. 00%and 22. 22%,respectively,and there was no sig-nificant difference (P>0. 05). There were no serious adverse reactions in the two groups. Conclusion: Xiaocuo decoction combined with 0. 025% tretinoin in the treatment of acne vulgaris has promising clinical efficacy with high safety.
