Quality Standard for Compound Yinchen Mixture
- VernacularTitle:复方茵陈合剂质量标准的建立
- Author:
Jianqing LIU
;
Qingfen WANG
;
Yixiang CAO
;
Rong ZHANG
- Publication Type:Journal Article
- Keywords:
Compound Yinchen mixture;
TLC;
HPLC;
Chlorogenic acid;
Geniposide
- From:
China Pharmacist
2016;19(4):790-792
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To establish the quality standard for compound Yinchen mixture. Methods:A TLC method was used to i-dentify Artemisiae scopariae Herba,Gardeniae Fructus, and Rhei Radix et Rhizoma in the mixture. An HPLC method was used to quan-titatively analyze the concentration of chlorogenic acid and geniposide. Results:The TLC spots were clear without any interference the negative control. The linear range of chlorogenic acid was 0. 04-0. 20 mg·ml-1 ,and that of geniposide was 0. 05-0. 25 mg·ml-1 . The average recovery of chlorogenic acid was 94. 4% with RSD of 1. 85%, and that of geniposide was 102. 2% with RSD of 1. 15%( n=6). Conclusion:The method is accurate,reliable,specific and reproducible,which can be used for the quality control of compound Yinchen mixtures.
