Correlation between time of fever onset and etiologies：a novel diagnostic strategy for fever of unknown origin
10.3760/cma.j.issn.1671-0282.2016.04.014
- VernacularTitle:不明原因发热中起热时间与病因诊断的关联性研究
- Author:
Xiaodong SHEN
;
Zhigang SHAN
;
Guoxin HAN
;
Hongju XIAO
;
Xin CHEN
;
Tanshi LI
;
Gang LIU
;
Haiyan ZHU
- Publication Type:Journal Article
- Keywords:
Fever of unknown origin;
Diagnosis;
Etiology;
Signs and symptoms;
Logistic regression analysis;
Retrospective study;
Correlation;
Time of fever onset
- From:
Chinese Journal of Emergency Medicine
2016;25(4):465-469
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the correlation between time of fever onset in the course of patients'illness and etiologies of fever of unknown origin (FUO).Methods A total of 1 570 patients with FUO admitted from January 2013 to December 2014 were retrospectively analyzed, and clinical data ( sex, age, time of fever onset) of 348 patients meeting FUO diagnosis criteria with definite etiology diagnosis and time of fever onset were collected for multivariate logistic regression analysis after bias check.Results No statistically significant bias was found between 348 selected cases and 1 570 overall cases in gender (χ2 =0.029, P=0.903) and age (t=-1.040, P=0.299), and multivariate logistic regression analysis showed positive correlation between fever onset during 13: 00-18: 00 and infection (P=0.044, B=1.275), 18:00-24: 00 and connective tissue diseases ( P =0.029, B =0.838 ) , and showed negative correlation between age and miscellaneous (P =0.010, B =-0.042).Conclusions Characteristics of fever onset time may have significant value in preliminary diagnosis and guiding the correct direction of final definite diagnosis by means of targeted examinations or diagnostic treatments.It is worth to be further studied and discussed.
