The correlation of inflammatory severity between appendiceal orifice inflammation and ulcerative colitis
10.3760/cma.j.issn.1007-5232.2016.03.006
- VernacularTitle:内镜下阑尾开口炎与溃疡性结肠炎炎症严重程度的关系
- Author:
Daqin ZHAN
;
Xing CHEN
;
Jing ZHANG
;
Ruijun MA
;
Rong WANG
;
Dongmei WANG
- Publication Type:Journal Article
- Keywords:
Ulcerative colitis;
Appendiceal orifice inflammation;
Skip lesion;
Retrospective study
- From:
Chinese Journal of Digestive Endoscopy
2016;33(3):155-159
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the correlation of inflammatory severity between appendiceal ori-fice inflammation(AOI)and ulcerative colitis(UC). Methods A retrospective analysis of the patients who were diagnosed as UC was conducted to investigate the correlation of the severity of inflammation between AOI and UC by linear trend test. Results The detective rate of UC during the above period was 2. 3%(991/ 42 928),with the patient number of 991.Appendiceal orifice observation did not perform in 45 cases due to patients reasons. In 946 patients,260 cases were diagnosed as having AOI,which accounted for 27. 5%of the total cases examined.AOI positive rates were significantly different between groups based on endoscopic severity standard(χ2 = 27. 39,P<0. 05),which was similar in moderate and severe group[30. 2%(109/ 361) VS 29. 8%(147/ 493),P>0. 0125],both significantly higher than that in mild group[4. 3%(4/ 92),P<0. 0125]. In linear regression analysis,regression coefficient was 0. 32,χ2return = 29. 48(P<0. 05)and χ 2partial =31. 66(P<0. 05),which proved a positive correlation between the two drawn existed but not a simple linear relationship. Conclusion AOI is a sign in some active UC patients. Its severity of inflammation can reflect the degree of inflammation in UC,which may offer a terminal point when treating a slice of UC individuals and giving a signal of its relapse.
