Early goal-directed therapy:status and renew
10.3760/cma.j.issn.1673-4912.2016.03.003
- VernacularTitle:目标导向治疗还要遵守吗？
- Author:
Huijie MIAO
;
Yucai ZHANG
- Publication Type:Journal Article
- Keywords:
Early goal-directed therapy( EGDT);
Severe sepsis;
Septic shock;
Mortality;
Children
- From:
Chinese Pediatric Emergency Medicine
2016;23(3):152-155
- CountryChina
- Language:Chinese
-
Abstract:
Early goal-directed therapy ( EGDT ) emerged as a novel approach for reducing septic shock mortality and the EGDT protocol requires invasive patient monitoring to guide resuscitation with intra-venous fluids.EGDT was incorporated into guidelines published by the international Surviving Sepsis Cam-paign,but remains controversial.Recently,large randomized trials showed that EGDT did not significantly de-crease mortality in patients with septic shock compared with usual care.Fliud resuscitation and monitoring is the most important in septic shock.Therefore the EGDT is still valuable in present stage.Further,development practical methods for accurately assessing optimal fluid administration is needed.
