Effect of external circulation of hyoertonic preconditioning on the cardiopulmonary function after coronary artery bypass grafting
10.3760/cma.j.jssn.1673-4904.2016.03.020
- VernacularTitle:高渗预充液体外循环对冠状动脉旁路移植术后的心肺功能影响研究
- Author:
Longjin ZHU
;
Shuaizhou LIU
;
Xiaohua LI
- Publication Type:Journal Article
- Keywords:
External circulatuon;
Hypertonic preconditioning;
Coronary artery bypass grafting;
Extravascular lung water;
Cardiopulmonary function
- From:
Chinese Journal of Postgraduates of Medicine
2016;39(3):261-264
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of external circulation of hypertonic preconditioning on the extravascular lung water in the early stage and cardiopulmonary function after coronary artery bypass grafting. Methods The clinical data of 82 patients who had undergone coronary artery bypass grafting in our hospital between January 2011 and December 2014 were reviewed and according to the different solutions given, they were divided into two groups (each with 41 cases). The patients in the control group were given crystalloid solution, and in the study group were given hypertonic crystalloid. The index during operation and postoperative index, COP and EVLW during different periods and the cardiopulmonary function of the two groups was compared. Results The plasma colloid osmotic concentration in study group was (42.16 ± 12.26) mmol/L, and higher than that in the control group, which was (2.16 ± 0.25) mmol/L, P<0.01. whereas the other intraoperative and postoperative indicators including cardiopulmonary bypass time, aortic crossclamp time, the number of vascular anastomosis, serum creatinine and blood urea nitrogen one day after the operation, and time of mechanical ventilation showed no significant differences (P > 0.05). COP and heart rate at T1 and T2 in the study group was significantly lower than that in the control group, with COP at T1 and T2 in the study group was (19.88 ± 2.47) and (21.36 ± 3.25) mmol/L, and (22.16 ± 2.97) and (23.65 ± 2.14) mmol/L in control group;and heart rate at T1 and T2 in the study group was respectively (83.65 ± 12.54) and (86.95 ± 11.52) times per minute and (95.32 ± 11.88) and (97.58 ± 10.54) times per minute in control group; the differences between the two groups were significant (P < 0.05). However, there were no significant differences shown in the MAP and CVP at any time points (P>0.05). Conclusions External circulation of hypertonic preconditioning can effectively improve the extravascular lung water in the early stage after coronary artery bypass grafting, yet produces no effect on the cardiopulmonary function.
