The mechanism of acute ischemic stroke in cancer patients
10.3760/cma.j.jssn.1673-4904.2016.03.022
- VernacularTitle:肿瘤导致急性缺血性脑卒中临床发作机制研究
- Author:
Jiacai LIN
;
Siting WU
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Cerebrovascular disorders;
TOAST tpying;
D-dimer
- From:
Chinese Journal of Postgraduates of Medicine
2016;39(3):268-270
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the mechanism of acute ischemic stroke in cancer patients. Methods The clinical TOAST type, laboratory examinations results, imaging examination results and pathology reports of the 96 patients with cancer and acute cerebral infarction were collected. Results According to TOAST mechanism, the main subtype was undetermined causes (41.67%, 40/96). Lung cancer took largest proportion (39.58%, 38/96). In the group of undetermined causes, adenocarcinoma was more common type than squamous. The imaging examination results could be classified into large artery type, large artery and small artery in same basin and multiple small arterys in different basins. We found the main type was multiple small arterys in different basins (52.50%, 21/40). The lever of D-dimer was high in our patients, especially in undetermined causes (P < 0.01). Conclusions Tumor-related acute cerebral infarction has its own uinque mechanism. Tumor is one kind of systemic diseases, which can promote thrombosis through increasing the lever of D-dimer. The cancer-related mechanism is the main mechanism underlying cancer- related stroke, and may become one of the most important mechanismsn in the pathogenesis of stroke in the near future.
