Research foundation of antioxidant therapy in cervical cancer

VernacularTitle:抗氧化系统在宫颈癌中的研究进展
Author: Ying PENG ; Jirong YUAN
Publication Type:Journal Article
Keywords: Uterine cervical neoplasms; Antioxidants; Treatment outcome
From: Chinese Journal of Postgraduates of Medicine 2016;39(3):286-288
CountryChina
Language:Chinese
Abstract: Cervical cancer was the most common gynecological malignant tumor, and endanger the lives of women. In recent years, research on antioxidant system confirmed that the antioxidant system of defects was closely related with the risk factors of cervical cancer. The lack of antioxidants that generates excessive reactive oxygen species, damaged the cervix cells. Human papilloma virus (HPV) infection was the main pathogenic factor of cervical cancer.Epidemiological studies had shown that including oxidative stress and antioxidant defects may prompt some auxiliary factors of HPV infection were finally for the development of cervical cancer. Because the oxidation has small side effects, safety, etc, so its anti-tumor effect was becoming more and more attention. Recently, on the antioxidant therapy in the treatment of cervical cancer research has made great achievements. This article expounds the antioxidant system defects and relationship between occurrence and development of cervical cancer, also reviewed the antioxidant therapy of cervical cancer research foundation and the latest clinical research.