Disease constitution analysis of 4 590 children with abnormalities in the blood cells
10.3760/cma.j.issn.1009-9921.2015.12.010
- VernacularTitle:儿童血细胞异常4 590例疾病构成分析
- Author:
Xinghong CHANG
;
Guoping HAO
;
Youcai FENG
- Publication Type:Journal Article
- Keywords:
Child;
Bone marrow cell morphology;
Diagnosis
- From:
Journal of Leukemia & Lymphoma
2015;24(12):743-745
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the significance of bone marrow cell morphology on clinical diagnosis of children hematopoietic diseases.Methods The data of bone marrow cell morphology in the bone marrow puncture specimens from 4 590 children admitted to Children' s Hospital of Shanxi Province from January 2009 to December 2014 were retrospectively analyzed.Results The proportion of infancy patients was the highest in 4 590 bone marrow specimens, accounting for 29.0 ％ (1 333/4 590), then that of the toddler age patients was second highest, accounting for 26.7 ％ (1 224/4 590).The constituent ratio of thrombocytopenic purpura (ITP) at the different ages was the highest.The most common diseases in bone marrow cell morphology diagnosis were in order of ITP, iron deficiency anemia (IDA), infectious bone marrow, leukemia (acute lymphoblastic leukemia, acute myeloid leukemia), aplastic anemia and so on.Conclusions Accurate analysis of bone marrow cell morphology is still the most basic and rapid approach in children with hematopoietic system disease, which has important value.Except hematopoietic system diseases, once fever of unknown origin, hepatosplenomegaly and enlargement of lymph nodes the patients should be early given bone marrow cell morphology check, early diagnosis and therapy.
