Lentinan combined with conventional antituberculous therapy for pelvic tuberculosis in women
10.3760/cma.j.issn.1673-4246.2016.01.007
- VernacularTitle:香菇菌多糖片联合常规抗结核疗法治疗女性盆腔结核
- Author:
Yujie YAO
;
Fang SUN
;
Xiaodan ZHANG
;
Han WEI
;
Xiaoyu DONG
- Publication Type:Journal Article
- Keywords:
Pelvic infection;
Tuberculosis;
Antitubercular agents;
Lentinan;
CA-125 antigen;
Female
- From:
International Journal of Traditional Chinese Medicine
2016;38(1):25-28
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the therapeutic effect of lentinan combined with conventional antituberculous therapy in women with pelvic tuberculosis.Methods A total of 90 women with pelvic tuberculosis were enrolled and recruited into a control group and a treatment group by random number table,45 in each group.The control group was treated with anti-tuberculosis program (2HRZE/4HRE),while the treatment group was treated with lentinan tablets on the basis of the control group.Both groups were treated for 6 months.Serum levels of carbohydrate antigen 125 (CA125) and erythrocyte sedimentation rates (ESRs) were determined before and after treatment,and the therapeutic effect was evaluated.Results After treatment,the serum CA125 level (28.61 ± 9.08 U/ml vs.39.72 ± 12.13 U/ml;t=4.919,P＜0.01) and the ESR (36.13 ± 8.33 mm/h vs.41.35 ± 12.45 mm/h;t=2.338,P＜0.05) in the treatment group were significantly lower than those in the control group.The negative rate of serum CA125 after treatment than before treatment in the treatment group (93.3％ vs.20.0％;X2=46.335,P＜0.01) and the control group (82.2％ vs.8.9％;X2=37.396,P＜0.01);but there was no difference in negative rate of serum CA125 after treatment between two groups (X2=1.6571,P=0.198).The total effective rate in the treatment group was significantly higher than that in the control group (93.3％ vs.77.8％;X2=4.406,P=0.036).Conclusion Lentinan combined with conventional antituberculous therapy is effective in treatment of pelvic tuberculosis in women.
