Advances in the roles of biomarkers in evaluating the severity and prognosis of severe pneumonia in children
10.3760/cma.j.issn.1673-4912.2015.12.014
- VernacularTitle:实验室监测指标对评估儿童重症肺炎病情及预后意义的研究进展
- Author:
Ting ZHANG
- Publication Type:Journal Article
- From:
Chinese Pediatric Emergency Medicine
2015;22(12):865-868
- CountryChina
- Language:Chinese
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Abstract:
Pneumonia is the primary cause of death in children under five-years old.About 2 million children younger than 5 years die of pneumonia each year worldwide,accounting for 19% of the total number of deaths.According to the survey in 2008,7% to 13% of the children with pneumonia were severe pneumonia.Currently,the early diagnosis and treatment of severe pneumonia is often difficult.In order to improve the early diagnosis an prognosis cognition level of severe pneumonia,here is to make a review on the recent literatures on the biomarkers like brain natriuretic peptide,D-Dimer,C-reactive protein,lactate,zinc,procalcitoin,prealbumin,platelet count,endothelin-1 and high mobility group box 1 in children with severe pneumonia.