Correlation of LATS2 mRNA and protein expression in oral squamous cell carcinoma
- VernacularTitle:口腔鳞癌中 LATS2基因 mRNA 与蛋白表达及其相关性
- Author:
Zengwen YUE
;
Xuanping CAO
;
Jinzhong LIU
;
Shubin WANG
;
Bo YAN
- Publication Type:Journal Article
- Keywords:
Oral squamous cell carcinoma(OSCC);
LATS2;
RT-PCR;
Western blot
- From:
Journal of Practical Stomatology
2016;32(3):432-433
- CountryChina
- Language:Chinese
-
Abstract:
RT-PCR and Western blot were used to detect the LATS2 mRNA and protein level in 57 cases of oral squamous cell carcinoma (OSCC)specimens and 12 normal oral mucosa tissues.LATS2 mRNA and protein were expressed in all the normal oral mucosa samples (100%),but only 47.4% (27 /57)and 42.1% (24 /57)in OSCC samples respectively with positive correlation of both(P <0.01),and were respectively correlated with the tumor differentiation degree and lymph node metastasis(P <0.05).
