Intestinal microecology and occurrence and development of type 2 diabetes mellitus
10.3867/j.issn.1000-3002.2016.05.001
- VernacularTitle:肠道微生态与2型糖尿病的发生和发展
- Author:
Linlin LI
;
Ye WANG
- Publication Type:Journal Article
- Keywords:
type 2 diabetes mellitus;
intestinal microbecology;
intestinal microbiota
- From:
Chinese Journal of Pharmacology and Toxicology
2016;30(5):483-490
- CountryChina
- Language:Chinese
-
Abstract:
Type 2 diabetes mellitus(T2DM)is a complicated endocrine disease caused by both genetic and environmental factors,many of which are unknown as far as for the pathogenesis of T2DM is concerned. In recent years,diabetes researchers have paid more attention to the intestinal microbiota. The discovery,verification and molecular mechanism of the intestinal microbiota related to T2DM are the focus of this article. The role of intestinal microecology in the development of T2DM is also reviewed,involving diet,chronic inflammation,short chain fatty acids,bile acids,the intestinal microbiota and circadian rhythm,and microRNA.
