The effects of amelogenin on the migration,adhesion and proliferation of periodontal ligament stem cells
10.3969/j.issn.1001-3733.2016.03.018
- VernacularTitle:釉原蛋白对牙周膜干细胞迁移、黏附及增殖的影响
- Author:
Peixun FENG
;
Shuang WANG
;
Yao LIU
;
Pei CAO
;
Kexiang LI
;
Haijuan ZHANG
- Publication Type:Journal Article
- Keywords:
Periodontal ligament stem cells(PDLSCs);
Amelogenin;
Migration;
Adhesion;
Proliferation
- From:
Journal of Practical Stomatology
2016;32(3):383-388
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the effects of amelogenin(AML)on the migration,adhesion and proliferation of periodontal liga-ment stem cells(PDLSCs).Methods:PDLSCs were cultured with AML at 0.25,50 amd 100 μg/ml respectively.The migration, adhesion and proliferation of the cells were examined by wound healing migration assay,transwell migration assay,attachment assay, MTT assay and cell counting,respectively.Results:AML induced the migration of PDLSCs in a dose-dependent manner(P <0.05), increased the adhesion and proliferation of PDLSCs(P <0.05).Conclusion:AML may promote the migration,adhesion and prolifer-ation of PDLSCs.
