Advances in direct-acting antiviral agents in treatment of chronic hepatitis C
10.3760/cma.j.issn.1674-2397.2015.06.015
- VernacularTitle:直接抗病毒药物在慢性丙型肝炎中的临床应用进展
- Author:
Qiang LI
;
Yuxian HUANG
;
Liang CHEN
- Publication Type:Journal Article
- Keywords:
Hepatitis C,chronic;
Antiviral agents;
Protease inhibitor;
Therapeutic uses
- From:
Chinese Journal of Clinical Infectious Diseases
2015;8(6):571-576
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, with the advances in life cycle of hepatitis C virus (HCV) and the approval of direct-acting antiviral agents (DAAs), great progress has been made in treatment of chronic hepatitis C (CHC).This article reviews the research progress of DAAs in CHC management, showing the possibility of the elimination of HCV infection by DAAs.DAAs have not been widely clinically used due to high medication costs, but can be used as a supplement for the combination therapy of pegylated interferon and ribavirin.
