Surgical treatment of epilepsy in tuberous sclerosis complex
10.3760/cma.j.issn.2095-428X.2015.24.004
- VernacularTitle:结节性硬化症相关癫(痫)的外科治疗
- Author:
Shiyong LIU
;
Wei LI
- Publication Type:Journal Article
- Keywords:
Tuberous sclerosis complex;
Refractory epilepsy;
Cortical tubes;
Surgical treatment
- From:
Chinese Journal of Applied Clinical Pediatrics
2015;30(24):1851-1854
- CountryChina
- Language:Chinese
-
Abstract:
Tuberous sclerosis complex (TSC) is a rare autosomal dominant neurocutaneous disease.Epilepsy is the most common manifestation.Studies show that even with a variety of antiepileptic drugs, more than 50％ of TSC related epilepsy are drug-resistant.Since cortical tubers are the main epileptogenic foci, resection surgery become an important treatment of intractable epilepsy in TSC.In recent years, with the development of electrophysiology and imaging technology, surgical treatment of epilepsy in TSC shows a great efficacy of controlling seizures and improving intelligence.Up to date, there are no standard procedures of surgical treatment for refractory epilepsy in TSC.This paper aimed to provide some instructions.
