Tumor vascular normalization improves cancer treatment efifcacy
10.3969/j.issn.1007-3969.2016.02.012
- VernacularTitle:血管正常化提高肿瘤治疗疗效
- Author:
Jing ZHANG
;
Wenchao ZHANG
;
Zijun QIAN
;
Beili GAO
;
Yi XIANG
- Publication Type:Journal Article
- Keywords:
Anti-angiogenesis therapy;
Vascular normalization;
Improvement;
Cancer treatment
- From:
China Oncology
2016;26(2):188-192
- CountryChina
- Language:Chinese
-
Abstract:
Therapeutic strategies targeting tumor angiogenesis have been approved for cancer therapy. Vasculature normalization induced by anti-angiogenic drugs can restore abnormal tumor vessels, and improve the tumor microenvironment characterized by hypoxia, extracellular acidosis, and high interstitial lfuid pressure, improve the cancer treatment results by chemoradiotherapy and immunotherapy.