Relationship Between Long-, Short-term Systolic Blood Pressure Variability and Renal Damage in Elder Population
10.3969/j.issn.1000-3614.2016.05.012
- VernacularTitle:长时和短时收缩压变异性指标与老年人群肾脏损害的关联研究
- Author:
Jihong SHI
;
Lu SONG
;
Chenrui ZHU
;
Hailiang XIONG
;
Yongzhi WANG
;
Chunhui LI
;
Hualing ZHAO
;
Yiming WANG
;
Shuohua CHEN
;
Shouling WU
- Publication Type:Journal Article
- Keywords:
Systolic blood pressure variability;
Elder population;
Glomerular ifltration rate;
Microalbuminuria
- From:
Chinese Circulation Journal
2016;31(5):467-471
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the relationship between long-, short-term systolic blood pressure variability (SBPV) and renal damage in elder population. Methods: Our research was conducted in the 3rd physical examination of healthy population from Kailuan group by cohort study. Cluster sampling was used by 25% ratio in subjects≥60 years of age to monitor their 24-hour ambulatory blood pressure and finally, 2464/3064 participants with inclusion criteria were recruited. SBPV indexes as standard deviation of systolic blood pressure (SSD), variability independent of the mean (VIM), maximum-minimum difference (MMD) and average real variability (ARV) were examined; renal damage indexes as estimated glomerular filtration rate (eGFR) and microalbuminuria (ALBU) were detected. Relationships between different long-term, short-term SBPV indexes and eGFR, ALBU were studied by multi-liner regression analysis. Results:①The mean age of 2464 participants was (67.41 ± 6.05) years including 1667 (67.7%) male and 797 (32.3%) female.②Multi-liner regression analysis indicated that different long-term SBPV indexes were not related to eGFR and ALBU; 24h SBPV in all 4 indexes and day-time SSD, MMD, ARV were negatively related to eGFR; 24h ARV and day-time MMD, ARV were positively related to ALBU; night-time SBPV indexes were not related to eGFR and ALBU.Conclusion: Different short-term SBPV indexes were, at certain point related to eGFR and ALBU
