Clinical Study on ModifiedYigongsan Formula Combined with Aidi-injection in the Treatment of Advanced Gastric Cancer
10.3969/j.issn.1005-5304.2016.06.010
- VernacularTitle:加味异功散方联合艾迪注射液治疗中晚期胃癌临床研究
- Author:
Yonghao LI
- Publication Type:Journal Article
- Keywords:
ModifiedYigongsan Formula;
Aidi-injection;
advanced gastric cancer
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2016;23(6):35-38
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical efficacy of ModifiedYigongsan Formula combined with Aidi-injection on advanced gastric cancer.Methods Totally 64 cases of patients with advanced gastric cancer were randomly divided into treatment group and control group with 32 cases in each group. Both groups were treated with Aidi-injection for intravenous drip, continuous infusion for 2 weeks. The treatment group was treated with Modified Yigongsan Formula, daily 1 agent, oral administration after lunch, for 4 weeks continuously; the control group did not take other medicine. The tumor markers (CEA, CA199), TCM syndrome score and physical condition score of the patients before and after treatment were observed.ResultsAfter treatment, the TCM syndrome score in the treatment group was significantly improved than that in the control group; the total effective rate was 84.38% (27/32) in the treatment group, and 43.75% (14/32) in the control group; the treatment group was significantly higher than that in the control group (P<0.05). The Karnofsky score of the treatment group was significantly higher than that of the control group (P<0.05). The tumor markers of two groups had no significant difference before and after treatment (P>0.05). Conclusion ModifiedYigongsan Formula combined with Aidi-injection on advanced gastric cancer tumor marker improvement was not obvious, but the improvement of TCM syndrome and physical condition of patients is very obvious.