Discussion on Establishment and Evaluation of Ulcerative Colitis Animal Models with Spleen-kidney Yang Deficiency Pattern Based on the Theory of “Combination of Disease with Syndrome”
10.3969/j.issn.1005-5304.2016.06.005
- VernacularTitle:基于“病证结合”理论探讨溃疡性结肠炎脾肾阳虚证动物模型建立与评价
- Author:
Jie ZHENG
;
Zebiao CAO
;
Ying ZHU
- Publication Type:Journal Article
- Keywords:
ulcerative colitis;
spleen-kidney yang deficiency;
combination of disease with syndrome;
animal models
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2016;23(6):16-18
- CountryChina
- Language:Chinese
-
Abstract:
Theory of “combination of disease with syndrome” has been widely used in the establishment and evaluation of experimental animal models. The ulcerative colitis animal models with spleen-kidney yang deficiency pattern were established based on the theory according to complex factors. These models were not only required to show the features of “disease” and “syndrome” at the macro characterization, but also combined with microscopic biological indicators and prescription test so as to make comprehensive evaluation. But the problems in the establishment and evaluation of “combination of disease with syndrome” models hindered further development, such as the weak connection between disease and syndrome, multiplicity of models, and limitations in evaluation standards. Therefore, further improvement in the establishment and evaluation of models will make great sense to better ulcerative colitis animal models with spleen-kidney yang deficiency pattern.
