Progress in research of hypoxia inducing factor-1, vascular endothelial growth factor and its receptor family with hypertensive disorder complicating pregnancy
10.3760/cma.j.issn.2095-4255.2016.03.018
- VernacularTitle:缺氧诱导因子-1和血管内皮生长因子及其受体家族对妊娠期高血压疾病发生的研究进展
- Author:
Tong JIANG
;
Fangcong LIU
;
Liying CAI
- Publication Type:Journal Article
- Keywords:
Hypertension,pregnancy-induced;
Hypoxia inducible factor-1;
Vascular endothelial growth factor
- From:
Chinese Journal of Endemiology
2016;35(3):231-234
- CountryChina
- Language:Chinese
-
Abstract:
Hypertensive disorder complicating pregnancy is a special disease during pregnancy,and it is the key reason for rising death rate of maternal and perinatal infants.Its etiology and pathogenesis are not yet fully elucidated.It is generally accepted that placenta damage plays a central role in hypertensive disorders complicating pregnancy.In recent years,studies have shown that hypoxia inducing factor-1 (HIF-1),vascular endothelial growth factor (VEGF)and its receptor family are important regulatory factors associated with hypertensive disorders complicating pregnancy.In this article,we discussed the relationship between the two factors and hypertensive disorders complicating pregnancy.
