Prognosis evaluation of intermittent high-volume on-line hemofiltration and hemodialysis in critically ill patients with acute kidney injury
10.3760/cma.j.issn.1673-4904.2015.12.002
- VernacularTitle:在线血液滤过与血液透析对合并急性肾损伤危重患者预后评估
- Author:
Bo ZHONG
;
Jiamei WEI
;
Yu NA
- Publication Type:Journal Article
- Keywords:
Kidney diseases;
Critical illness;
Renal dialysis;
Hemodiafiltration;
Prognosis
- From:
Chinese Journal of Postgraduates of Medicine
2015;38(12):862-866
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare clinical prognosis between intermittent high-volume predilution on-line hemofiltration (HF) and standard intermittent hemodialysis (HD) in critically ill patients with acute kidney injury (AKI).Methods This was a prospective,randomized,controlled single-centre clinical study.The mortality and recovery rate of kidney function were compared in critically ill adult patients with AKI between HF group (using intermittent high-volume predilution on-line HF,50 cases) and HD group (standard intermittent HD,45 cases).The prognosis of 60 d was followed up,including 60-day all-cause mortality,in-hospital all-cause mortality and recovery of kidney function.Results There were no statistical differences in basic clinical characteristics between 2 groups (P ＞ 0.05).The results of 60-day' follow-up showed,the mortality in HF group was 68.0％ (34/50),and in HD group was 82.2％ (37/45).There was statistical difference (risk ratio 0.75,95％ CI 0.80-1.28,P =0.036).There were no statistical differences in the in-hospital mortality and recovery rate of kidney function (P ＞ 0.05).There was no statistical difference in complication rate between 2 groups (P＞ 0.05).Conclusion The mortality is significantly lower in critically ill patients with AKI treated with intermittent high-volume predilution on-line HF,compared those treated with standard intermittent HD.
