Bacterial translocation:the core of gut microbiota dysbiosis in patients with short bowel syndrome
10.3760/cma.j.issn.1673-9752.2015.12.018
- VernacularTitle:肠道细菌移居:短肠综合征肠道微生态紊乱的核心
- Author:
Shengxian FAN
;
Yousheng LI
- Publication Type:Journal Article
- Keywords:
Short bowel syndrome;
Gut microbiota;
Bacterial translocation
- From:
Chinese Journal of Digestive Surgery
2015;14(12):1059-1062
- CountryChina
- Language:Chinese
-
Abstract:
The human gastrointestinal tract is colonized by complex and diverse microbiota which maintains an ecological balance under normal circumstances.Short bowel syndrome causes damage to the normal flora which predisposes the patient to colonic dysbacteriosis and small intestine bacterial overgrowth.Small intestine bacterial overgrowth may lead to digestive and absoptive disfunctions, mucosal inflammation, and may delay or prevent weaning from total parenteral nutrition.Moreover, small intestine bacterial overgrowth may be one of the causes of intestinal failure-associated liver disease, and eventually lead to various body dysfunctions.In this review, the bacterial translocation in short bowel syndrome were summarized, providing the theoretic proofs to treatment and prevention.
