Roles of cell signaling pathways in thyroid carcinoma
10.3760/cma.j.issn.1673-422X.2015.12.008
- VernacularTitle:细胞信号转导通路在甲状腺癌中的作用
- Author:
Yingkai XU
;
Jie HU
;
Wei LIU
- Publication Type:Journal Article
- Keywords:
Thyroid neoplasms;
Signal transduction pathways
- From:
Journal of International Oncology
2015;42(12):911-915
- CountryChina
- Language:Chinese
-
Abstract:
The intracellular signal transduction pathways play an important role in the occurrence and development of thyroid cancer.Mitogen activated protein kinase (MAPK) signal transduction pathway,phosphatidylinositol 3-kinase (PI3K)-AKT pathway,NF-κB pathway and RASSF1-MST1-FOXO3 pathway affect the occurrence and development of thyroid cancer by modulating the activity and expression of specifical proteins,and determine the growth and apoptosis of thyroid cancer cells.
