Research progress of resveratrol on the prevention and treatment of colorectal cancer
10.3760/cma.j.issn.1673-422X.2016.01.019
- VernacularTitle:白藜芦醇用于预防和治疗结直肠癌的研究进展
- Author:
Jiahui XU
;
Deying LIU
;
Zhijun XU
;
Wenxia MA
;
Qingling ZHANG
- Publication Type:Journal Article
- Keywords:
Colorectal neoplasms;
Resveratrol
- From:
Journal of International Oncology
2016;43(1):67-70
- CountryChina
- Language:Chinese
-
Abstract:
Recent studies show that resveratrol is characterized with its antioxidative and anti-inflammatory effects, and plays an important role in the prevention and treatment of colorectal cancer through modulating intracellular carbohydrate and ceramide metabolism, activating tumor suppressors such as activator of transcription 3 and peroxisome proliferators-activated receptor γ, down-regulating the expression of kirsten rat sarcoma viral oncogene and inhibiting the epithelial-to-mesenchymal transition process of cancer cells.In addition,resveratrol exhibits its broad application prospects in combination therapy.
