Relation between macroscopic type and cellular origin of intrahepatic cholangiocarcinoma
10.3760/cma.j.issn.1673-4203.2016.02.015
- VernacularTitle:肝内胆管癌的大体类型与细胞来源的关系
- Author:
Mintuo WANG
;
Zhigang LIU
;
Shenglin CHEN
;
Xiaoyi WANG
;
Lixia SUN
- Publication Type:Journal Article
- Keywords:
Biliary tract eoplasms;
Liver neoplasms;
Cells;
Identification
- From:
International Journal of Surgery
2016;43(2):120-124
- CountryChina
- Language:Chinese
-
Abstract:
Intrahepatic cholangiocarcinoma,which occurrence and development involved kinds of cells and genes changes,is a vital part of the primary carcinoma of liver.The cellular origin may includes bile duct epithelial cells,hepatic stem cells and hepatic cells.The macroscopic type may includes:nass-forming types,periductal infiltrating types,intraductal growth types.The fact was revealed that different macroscopic type of intrahepatic cholangiocarcinoma has different clinical features,outcomes and prognosis.The author reviewed recently published studies covering various aspects of intrahepatic cholangiocarcinoma,focusing especially on the macroscopic subtypes and related cell features,to discover the relaticn between macroscopic type and cellular origin of intrahepatic cholangiocarcinoma and better understand the pathogenesis of intrahepatic cholangiocarcinoma.