Advances in the research of chemotherapy for colorectal cancer
10.3760/cma.j.issn.1673-4203.2015.11.022
- VernacularTitle:结直肠癌化疗增敏性研究进展
- Author:
Haixin LU
;
Zhihui HUANG
;
Jiaya CHEN
;
Liping MO
;
Qichao LI
;
Tianyu LI
- Publication Type:Journal Article
- Keywords:
Colorectal neoplasms;
Cell cycle;
Apoptosis;
Treatment outcome;
Review
- From:
International Journal of Surgery
2015;42(11):789-792
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, chemotherapy is an important treatment for colorectal cancer, but the therapeutic effect of chemotherapy drugs is still poor, adverse reactions, and there are individual differences, studies have found that chemotherapy sensitizer in colorectal cancer is important, it is not only can improve the efficacy of chemotherapy drugs can reduce the toxicity of the neoadjuvant chemotherapy is to becomne a research focus in recent vears.Chemotherapy sensitizer will lead people to explore various combinations of different drugs and chemotherapy for the treatment of diseases and bring better outcomes, it will usher in a new era.The efficacy, mechanism, research status and safety of the colorectal cancer for enhancing its chemotherapy sensitivity of these representative drugs were reviewed in these article.
