Biocompatibility of bone marrow mesenchymal stem cells on acellular collagen matrix double-layer material
10.3760/cma.j.issn.1673-4181.2016.01.004
- VernacularTitle:脱细胞胶原基质双层材料与骨髓间充质干细胞的生物相容性研究
- Author:
Wenbin NAN
;
Zhihao XU
;
Yongxue WANG
;
Hongli CHEN
- Publication Type:Journal Article
- Keywords:
Bone marrow mesenchymal stem cells;
Biocompatibility;
Acellular collagen matrix double-layer material
- From:
International Journal of Biomedical Engineering
2016;39(1):16-19
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the biocompatibility of bone marrow mesenchymal stem cells (BMSCs) on acellular collagen matrix double-layer material.Methods BMSCs with acellular collagen matrix double-layer material were trained as experimental group,while separately cultured BMSCs as control group.The growth and proliferation of BMSCs on acellular collagen matrix double-layer material were investigated.Scanning electron microscope was used to observe the adherence of cells,and cell vitality was detected by CCK-8 method.Results The acellular collagen matrix double-layer material did not influence the growth and proliferation of BMSCs.The difference between the growth curves of experimental group and control group was not significant (P＞0.05).Conclusions The acellular collagen matrix double-layer material has acceptable biocompatibility.This research provides a scientific basis for the application of this composite material.
