Research progress on different methods of decellularization in tissues and organs
10.3760/cma.j.issn.1673-4181.2015.05.011
- VernacularTitle:组织及器官脱细胞方法的研究进展
- Author:
Yuan JIANG
;
Hongcan SHI
- Publication Type:Journal Article
- Keywords:
Extracellular matrix;
Tissue engineering;
Decellularization;
Scaffolds
- From:
International Journal of Biomedical Engineering
2015;38(5):300-305
- CountryChina
- Language:Chinese
-
Abstract:
Biologic scaffold materials derived from decellularized tissues and organs have been successfully used in tissue engineering and regeneration medicine.Decellularization methodology varies according to the differences of the origin,tissue density,composition,geometric and biologic properties of the tissue.Optimal decellularization method should be developed on the basis of complete cell content removal with the preservation of extracellular matrix (ECM) integrity and bioactivity.In this article,an overview of decellularization methods and their effect upon acellular bracket structure and composition are presented.
