Modified endoscopic resection of duodenal major papillary adenoma
10.3760/cma.j.issn.1007-5232.2015.11.005
- VernacularTitle:十二指肠乳头腺瘤内镜下乳头改良切除术的临床研究
- Author:
Jun CAO
;
Yunhong LI
;
Yuling YAO
;
Qibin HE
;
Han WU
;
Xiaoping ZOU
- Publication Type:Journal Article
- Keywords:
Adenoma;
Duodenal major papillary;
Endoscopic resection;
Modified method
- From:
Chinese Journal of Digestive Endoscopy
2015;32(11):734-738
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess feasibility and advantages of the improved endoscopic resection of duodenal major papillary.Methods A total of 56 cases were collected in Drum Tower Hospital from October 2007 to December 2012, which were diagnosed as duodenal major papillary adenoma or carcinoma in situ, where tumor didn't extend to the biliary or pancreatic duct by the endoscopic ultrasonography, intraductal ultrasonography or histology of biopsy specimens.The diameters of these adenoma ranged from 0.3 cm to 5.0 cm.Twenty-four lesions were resected by routine endoscopic method and 32 lesions were removed by modified endoscopic method.All patients underwent ERCP and biliary and/or pancreatic stents were placed.Results En bloc resection rate was significantly higher in modified group(87.5％ ,28/32) than that in routine group (60.9％, 14/23, P ＜ 0.05).There were no significant differences in complete resection rates (93.8％ ,30/32 VS 87.0％, 20/23;P ＞0.05), or in the amount and difficulty of pancreaticobiliary stenting(P ＞ 0.05)between modified group and routine group.Short-term complication occurrence in modified group was lower than that of the routine group(15.6％ ,5/32 VS 41.6％, 10/24, P ＜ 0.05), but long-term complication occurrence showed no significant difference.There was no significant difference in recurrence rate between two groups[7.1％ (2/28) VS 15.0％ (3/20) ,P ＞0.05].Conclusion Endoscopic resection of duodenal major papillary adenoma with a modified method shows more therapeutic effect.
