Balloon dilatation therapy for treating dysphagia after brainstem stroke: A fMRI study
10.3760/cma.j.issn.0254-1424.2015.012.002
- VernacularTitle:脑干卒中后吞咽障碍患者改良导管球囊扩张治疗中枢调控机制的fMRI研究
- Author:
Xiaomei WEI
;
Zulin DOU
;
Shaofeng ZHAO
;
Chunqing XIE
;
Wusheng LIN
;
Yujue WANG
- Publication Type:Journal Article
- Keywords:
Balloon dilatation therapy;
Dysphagia;
Brainstem stroke;
fMRI
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2015;37(12):892-898
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effects of modified balloon dilatation therapy for treating upper esophageal sphincter dysfunction after a brainstem stroke.Methods Ten healthy adult volunteers and 20 dysphagic patients with upper esophageal sphincter dysfunction after a brainstem stroke were recruited.The 20 patients were divided into a balloon dilatation therapy group of ten who were treated with catheter balloon dilatation therapy, and a control group of ten who received conventional therapy.All were given block-designed task fMRI scans guided by a matched visual presentation system before and after the treatment.Results Widespread activation was observed in both hemispheres, including the bilateral cerebral cortex, the brainstem and the cerebellum, but the activated areas were significantly smaller in the stroke patients before treatment.After the treatment, seven patients in the balloon dilatation group were totally orally fed, while only three patients in the control group recovered totally oral intake.After dilatation, significantly more regions were activated, including the anterior cingulate, insula, supplementary motor area, precuneus and the frontal lobe.They were activated with relatively low voxels in the treatment group, while in the control group significant activation was observed only in the precuneus after treatment.Conclusion Modified balloon dilatation therapy can increase activation of the cortex and subcortical structures related to swallowing, promoting better swallowing function.
